7. Chondro Protection
Another first from Biotics Research was the concept of Chondro-Protection via
supplementation. In the early 1980's, at the request of a cutting-edge chiropractic physician, Biotics research
began researching glyucosaminoglycans (GAGs). We soon focused on Chondroitin sulfates (CS), large, heterogeneous
biological polymers used by the body to maintain proper elastic integrity within tissues. The chief GAG of
cartilage is CS, a repeating disaccharide, specifically glucuronic acid and sulfated
N-acetylglucosamine.
Biotics learned that the benefits of CS were enormous. During the repair of
injured connective tissue, CS synthesis precedes collagen synthesis and is essential for proper healing.
Additionally, CS are structural components of vascular intima, giving strength and elasticity to blood vessels. We
also learned that the aging process causes many changes in CS patterns in cartilage. CS are gradually replaced by
other GAGs, affecting vascular permeability as well. In addition, the normal synthesis of CS can be inhibited by
nutritional deficiencies, and by the use of anti-inflammatory drugs such as corticosteroids, salicylates, gold
salts, ibuprofen, phenylbutazone and other NSAIDs. The benefits of Chondroitin sulfate for patients with
osteoarthritis have been well documentedas have the cardio protective benefits.
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